The nature of managing clinical research has evolved greatly since the initial clinical trial management systems (CTMS) and other early eClinical technologies were introduced. As the traditional trial paradigm has shifted, new technologies have been introduced and existing ones have evolved to keep up with the industry. As trial operators look to the future of clinical research, it’s imperative that they unify their trial management solutions to create a flexible and agile response. This paper will explore the ways that unifying your eClinical stack can help future-proof your clinical trials.